Phytochemicals Analysis, In Vitro Antibacterial Activities of Extracts, and Molecular Docking Studies of the Isolated Compounds from Melhania zavattarii Cufod Leaves

Table 6

Drug-likeness property of compounds 1 and 2 predicted by Swiss ADME software.

Compounds	Formula	Mol. wt. (g/mol)	NRB	NHA	NHD	TPSA (Å^2)	LogP (cLogP)	Lipinski’s rule of five violation	Bioavailability score
1	C46H80O2	665.13	16	2	—	26.30	12.42	2	0.17
2	C40H56O2	568.87	10	2	2	40.46	12.42	2	0.17
Chloramphenicol	C11H12Cl2N2O5	323.13	7	5	3	115.38	0.73	0	0.55

Note. NHD = number of hydrogen donor, NHA = number of hydrogen acceptor, NRB = number of rotatable bonds, and TPSA = total polar surface area and LogP (cLogP) = octanol-water partition coefficient.