Antidepressant and Anxiolytic Potentials of the Chewing Stick, Salvadora persica

Table 3

Effect of Sp extracts in the FST model.

Groups	Treatment (drugs and dosage)	Duration of the immobility period in seconds	Duration of swimming time in seconds
I	0.09% n/saline (p.o)	165.33 ± 3.57	134.66 ± 5.13
II	FLX, 30 mg/kg (p.o)	49.33 ± 1.49	210.66 ± 3.97
III	Sp (AE) 500 mg/kg	47.83 ± 2.7	202.33 ± 7.75
IV	Sp (EAE) 500 mg/kg	46.16 ± 3	206.83 ± 5.3

Each value represents mean ± SEM (n = 6).  < 0.005, in comparison with the control. n/saline, normal saline; FLX, fluoxetine; Sp (AE), aqueous extract of Salvadora persica; Sp (EAE), ethyl acetate extract of Salvadora persica.