Antidepressant and Anxiolytic Potentials of the Chewing Stick, Salvadora persica

Table 4

Effect of Sp extracts on the light and dark model.

Groups	Treatment (drugs and dosage)	Time spent in the light box	Time spent in the dark box	No. of crossings
I	0.09% n/saline (p.o)	129.33 ± 13.57	170.67 ± 12.13	14.65 ± 3.62
II	DZP, 1 mg/kg (p.o)	201.32 ± 11.44	98.68 ± 8.97	28.24 ± 2.68
III	Sp (AE) 500 mg/kg	198.66 ± 12.73	101.34 ± 10.14	25.38 ± 2.24
IV	Sp (EAE) 500 mg/kg	212.6 ± 13.32	87.4 ± 9.32	26.92 ± 3.12

Each value represents the mean ± SEM (n = 6).  < 0.001, in comparison with control; n/saline, normal saline; DZP, diazepam; Sp (AE), aqueous extract of Salvadora persica; Sp (EAE), ethyl acetate extract of Salvadora persica.