Occurrence of Type 1 Diabetes in Graves' Disease Patients Who Are Positive for Antiglutamic Acid Decarboxylase Antibodies: An 8-Year Followup Study

Table 2

Baseline characteristics of the patients with positive GAD antibodies including their antibody titers.

Case		Age at entry	Sex	duration; (yr)	GADA; (LBA); 0	GADA; (RIA); u/ml; <1.5	IA-2Ab; 0	TRAb; (%); <10.0	TGHA; (X); <400	MCHA; (X); <400	HbA1c; (%); 4.3–5.8	GTT
1	*	42	M	21	>1.300	6090	0.024	63.5		400000	5.7	DM
2		21	F	0	>1.128	>256	neg			400		normal
3	*	27	F	13	0.928	855	neg	21.5		400000	5.0
4		50	F	11	0.790	21.4	neg	7.2	400	100000		IGT
5		26	F	0	0.192	2.6	neg	6.7	1600	25600		normal
6		23	F	5	0.076		neg	24.2		100000
7		25	F	4	0.073	3.3	neg	29.5		400000	4.4	normal
8		42	F	2	0.062	0.5	neg	21.1			4.9
9		25	M	6	0.047	<0.4	0.083	7.0		6400	3.9
10		42	F	12	0.027	<0.4	neg	12.5			4.8

Figures at the bottom of the items are reference values.
*Cases 1 and 3 developed T1D.
neg: negative.
Age: age at examination of GAD antibodies.
TRAb: TSH receptor antibodies, TGHA: thyroglobulin hemagglutination, MCHA: microsome hemoagglutination.