Journal of Thyroid Research / 2011 / Article / Tab 4

Research Article

First- and Second-Trimester Reference Intervals for Thyroid Hormones during Pregnancy in “Rhea” Mother-Child Cohort, Crete, Greece

Table 4

Thyroid clinical entities in the general population of Rhea mother-child cohort based on: (i) the manufacturer’s and (ii) the derived reference limits.

TrimesterReference limitsNormal thyroid function (%)aSubclinical hypothyroidism (%)bClinical hypothyroidism (%)cSubclinical hyperthyroidism (%)dClinical hyperthyroidism (%)e

1stManufacturer386 (84.3)6 (1.3)0 (0)48 (10.5)7 (1.5)
Rhea cohort371 (81.0)31 (6.8)0 (0)1 (0.2)10 (2.2)
2ndManufacturer680 (86.6)18 (2.3)1 (0.1)61 (7.7)1 (0.1)
Rhea Cohort653 (82.2)47 (5.9)0 (0)18 (2.3)9 (1,1)

aTSH between reference limits and free T4 between reference limits.
bTSH over the upper limit of reference limits and free T4 between reference limits.
cTSH over the upper limit of reference limits and free T4 under the lower limit of reference limits.
dTSH under the lower limit of reference limits and free T4 between reference limits.
eTSH under the lower limit of reference limits and free T4 over the upper limit of reference limits.

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