Invariant NKT Cell Lines Derived from the NOD·H2h4 Mouse Enhance Autoimmune Thyroiditis
Figure 3
In vitro response of iNKT cells to thyroglobulin. A 72-hour proliferation assay was performed in response to 45 μg/mL of thyroglobulin. [3H]-thymidine incorporation was used as an indicator of stimulation response. Both cell lines showed a significantly higher proliferation in response to thyroglobulin. A few cells also proliferated in response to Ovalbumin (Ova). Results are expressed as mean counts/4 minutes of [3H]-thyrmidine uptake. (Representative of 3 independent experiments).
