Journal of Thyroid Research / 2012 / Article / Fig 4

Clinical Study

Changes of TSH-Stimulation Blocking Antibody (TSBAb) and Thyroid Stimulating Antibody (TSAb) Over 10 Years in 34 TSBAb-Positive Patients with Hypothyroidism and in 98 TSAb-Positive Graves’ Patients with Hyperthyroidism: Reevaluation of TSBAb and TSAb in TSH-Receptor-Antibody (TRAb)-Positive Patients

Figure 4

Clinical course of one of the 2 patients, who had TSAb-positive Graves’ hyperthyroidism and then developed TSBAb-positive hypothyroidism (Table 1, IId). A 40-year-old woman with TSAb-positive Graves’ hyperthyroidism developed TSBAb-positive hypothyroidism. She had TSAb-positive Graves’ hyperthyroidism ((a), ) with undetectable serum TSH ((b), ●) and then developed TSBAb-positive hypothyroidism ((b), ) with high serum TSH ((b), ●). TSAb was dominant initially ((a), ), and then TSBAb became dominant ((b), ). TBII ((b), ∘) reflects TSBAb- and TSAb-activity. A patient with TSAb-positive Graves’ hyperthyroidism developed TSBAb-positive hypothyroidism. She was treated with MMI and then with T4.
182176.fig.004a
(a)
182176.fig.004b
(b)

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