Pattern and Risk Factors of Central Compartment Lymph Node Metastasis in Papillary Thyroid Cancer: A Prospective Study from an Endocrine Surgery Centre

Table 2

Histopathological features; 𝑛=47 (% age).

Thyroid
Mean tumor size (cm) ± SD (range)	3.57 ± 2.42 (0.3–12)
Tumor staging
(i) T1	4 (8.5)
(ii) T2	19 (40.4)
(iii) T3	11 (23.4)
(iv) T4	13 (27.7)
Papillary microcarcinoma	8 (17)
PTC subtypes
(i) Classical variant (CV)	35 (74.5)
(ii) Follicular variant (FV)	8 (17)
(iii) Oncocytic variant (OV) [20]	1 (2.1)
(iv) Tall cell variant (TCV)	3 (6.4)
Laterality
(i) Right side	29 (61.7)
(ii) Left side	18 (38.3)
Multicentricity	18 (38.3)
Bilaterality	9 (19.1)
Extrathyroidal extension	13 (27.7)
Lymph nodes
Overall lymph nodes metastasis	30 (63.8)
Overall central compartment lymph nodes metastasis (CCM)	28 (59.6)
(i) Bilateral CCM	17 (60.72)
(ii) Isolated ipsilateral CCM	9 (32.14)
(iii) Isolated contralateral CCM	2 (7.14)
Overall lateral compartment lymph nodes metastasis (LLNM; 𝑛=19)	19 (100)
(i) Ipsilateral LLNM	15 (78.95)
(ii) Bilateral LLNM	3 (15.8)
(iii) Contralateral LLNM	1 (5.3)
Final pathological nodal staging (TNM-classification)
(i) pN0	25 (53.2)
(ii) pN1a	3 (6.4)
(iii) pN1b	19 (40.4)
Skip lateral metastasis (𝑛=19)	2 (10.5)
Skip contralateral central lymph node metastasis (𝑛=47)	2 (4.3)