Recombinant Human Thyrotropin-Aided Radioiodine Therapy in Patients with Metastatic Differentiated Thyroid Carcinoma
Figure 3
Treatment of a 73-year-old patient with Hürthle cell carcinoma. (a) rxWBS taken 48 hrs after the first application of 5.5 GBq of 131-I THW-aided RIT in 1997: pathologic uptake is visible in the thyroid bed, in the 4th thoracic vertebra (Th4), and in the lungs bilaterally. (b) An rxWBS (following a fifth RIT after hormone withdrawal with 7.4 GBq of 131-I in 2001) shows regression of metastatic disease: pathologic uptake in the lungs is no longer visible; the foci of uptake in Th4 appear to be smaller and less intense; cumulative uptake of RAI is 2%. (c) An rxWBS (following a second rhTSH-aided RIT with 7.4 GBq of 131-I in 2002) shows regression of metastatic disease: the foci of uptake in Th4 appear to be smaller and less intense; cumulative uptake of RAI is 0.05%.
