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Journal of Thyroid Research
Volume 2013 (2013), Article ID 398194, 5 pages
http://dx.doi.org/10.1155/2013/398194
Clinical Study

Thyroid Lobectomy Is Associated with Excellent Clinical Outcomes in Properly Selected Differentiated Thyroid Cancer Patients with Primary Tumors Greater Than 1 cm

1Endocrinology Service, Universidade Federal do Rio de Janeiro, Rua Rodolpho Paulo Rocco 255, Cidade Universitária Ilha do Fundão, 21941-913 Rio de Janeiro, RJ, Brazil
2Endocrinology Service, Instituto Nacional do Cancer, Praça da Cruz Vermelha 23, Centro, 20230-130 Rio de Janeiro, RJ, Brazil
3Surgery Service, Universidade Federal do Rio de Janeiro, Rua Rodolpho Paulo Rocco 255, Cidade Universitária Ilha do Fundão, 21941-913 Rio de Janeiro, RJ, Brazil
4Head and Neck Service, Instituto Nacional do Cancer, Praça da Cruz Vermelha 23, Centro, 20230-130 Rio de Janeiro, RJ, Brazil
5Endocrinology Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA

Received 25 June 2013; Revised 27 September 2013; Accepted 1 October 2013

Academic Editor: Gary L. Francis

Copyright © 2013 Fernanda Vaisman et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background and Objective. An individualized risk-based approach to the treatment of thyroid cancer is being extensively discussed in the recent literature. However, controversies about the ideal surgical approach remain an important issue with regard to the impact on prognosis and follow-up strategies. This study was designed to describe clinical outcomes in a cohort of low and intermediate risk thyroid cancer patients treated with thyroid lobectomy. Methods. Retrospective review of 70 patients who underwent lobectomy. Results. After a median follow-up of 11 years, 5 patients (5/70, 7.1%) recurred and 5 had a completion for benign lesions, while 60 patients (86%) continued to be observed without evidence for disease recurrence. Suspicious ultrasound findings were significantly more common in patients that had structural disease recurrence (100% versus 4.3%, ). Furthermore, a rising suppressed Tg value over time was also associated with structural disease recurrence (80% versus 21.5%, ). After additional therapy, 99% of the patients had no evidence of disease. Conclusions. Properly selected thyroid cancer patients can be treated with lobectomy with excellent clinical outcomes.