The Hypothalamic-Pituitary-Thyroid Axis in Infants and Children: Protection from Radioiodines

Table 3

Thyroid gland weights and thyroidal iodide stores in infants, children, and adults.

Subject	Thyroid weight (g)	Thyroidal iodide (mg/g)	Thyroidal iodide (mg)	Location	Reference
Adult males (𝑛=50)	10±2 SD; (5.6 to 17.7)	1.4±0.7 median, SD; (0.42 to 3.43)	15±8; (4 to 37)	Venezuela	[20]
Age 16 to 85 years, range of mean values (𝑛=83)	13 to 15.3	0.32 to 0.67	3.9 to 8.3	Russia	[21]
Age less than 16 years, 8 years average age (𝑛=5)	6.1±1.0 SE	0.24±0.08 SE	1.5±0.52 SE	Russia	[21]
Young adults (𝑛=8)	14.5±1.2 SE; (11.1 to 20.3)	0.97	15.0±1.5 SE; (9.0 to 23.6)	United States	[22]
Newborns
Less than 13-day-old term newborns (𝑛=4)	0.74±0.74 SD	0.060±42.3 SD	0.04	Italy	[23]
Gestation age 22 to 34 weeks preterm (𝑛=28)	0.61±0.35 SD	0.042±0.04 SD	0.03	Italy	[23]
Less than 30-day-old near-term newborns (𝑛=15)	0.93±0.4 SD	0.096±0.034 SD	0.09	Yugoslavia	[24]
Preterm newborns, under 10 days of age (𝑛=9)	—	0.092±0.01 SE; 0.049 to 0.166	—	Belgium	[25]
Preterm newborns, under 10 days of age (𝑛=8)	—	0.270±0.05 SE; 0.094 to 0.493	—	Canada	[25]
Newborns (𝑛=13)	1.0	—	0.292±0.05 SE	Canada	[26]
Preterm newborns (𝑛=17), under 20 hrs of age*, 1–3 days of age**, and 10 days to 7 weeks of age	0.42 to 1.2	0.06±0.05^∗; 0.09±0.05^∗∗; 0.26±0.05	—	France	[27]

The use of ** and * is associated with ages of newborns shown to the left, in column 1.