Short Course High Dose Radiotherapy in the Treatment of Anaplastic Thyroid Carcinoma

Table 5

Major radiation series comparing outcomes of anaplastic thyroid carcinoma.

Author	Intent	Median radiation dose	Resection	Fractionation	Local control	Chemotherapy	Radiation duration	Median survival
Wang et al. [13]	Definitive	60 Gy (45–66)	61%	Once daily or bid	94% (6 months)	No	4–6 weeks	11.1 months
	Palliative	40 Gy (split course)	50%	Once daily	65% (6 months)	16% (prior to or during)	4–6 weeks	3.2 months
de Crevoisier et al. [14]	Definitive	40 Gy (later boost to 50–55 Gy)	71%	Bid	68% (45 median FU)	Prior to and after	3-4 weeks	10 months (both arms)
	Palliative	40 Gy (later boost to 50–55 Gy)	50%	Bid	68% (45 median FU)	Prior to and after	3-4 weeks
Dumke et al. [15]	Both	50 Gy (6–60.4)	80%	Daily or bid	Unknown	15%	Unknown	5 months; if >50 Gy; 10.5 months
Stavas et al.	Definitive	54 Gy (49.5–62.5)	89%	Daily	89% (at time of death)	88% (concurrent)	23.5 days (13–36)	14.2 months
	Palliative	54 Gy (40–57)	75%	Daily	75% (at time of death)		26 days (22–37)	6.4 months