Research Article
Cardiovascular Risk Factors in Subclinical Hypothyroidism: A Case Control Study in Nepalese Population
Table 1
Characteristics of the study subjects.
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Variables | Subclinical hypothyroid (SH) (cases) () |
Euthyroid (controls) () | value (total) | SH with TSH <10 mIU/L () | SH with TSH ≥10 mIU/L () | value | Total () |
| Age (years) | 42.23 ± 11.15 | 38.60 ± 10.07 | 0.202 | 41.14 ± 10.92 | 41.14 ± 10.92 | 1.0 | BMI (Kg/m2) | 23.87 ± 1.91 | 26.01 ± 2.51 | <0.001 | 24.51 ± 2.32 | 24.11 ± 1.66 | 0.422 | Systolic BP (mmHg) | 119.6 ± 5.98 | 124.2 ± 6.37 | <0.001 | 120.98 ± 6.42 | 121.46 ± 6.06 | 0.457 | Diastolic BP (mmHg) | 80.66 ± 5.86 | 85.4 ± 5.09 | <0.001 | 82.08 ± 6.03 | 79.12 ± 6.05 | <0.001 | Free T3 (pmol/L) | 4.82 ± 0.48 | 4.32 ± 0.3 | <0.001 | 4.67 ± 0.49 | 5.11 ± 0.58 | <0.001 | Free T4 (pmol/L) | 10.54 ± 0.85 | 9.47 ± 0.28 | <0.001 | 10.22 ± 0.88 | 12.06 ± 2.0 | <0.001 | TSH (mIU/L) | 7.73 ± 1.14 | 14.09 ± 3.48 | <0.001 | 9.63 ± 3.61 | 2.35 ± 1.07 | <0.001 | Total cholesterol (mg/dL) | 191.74 ± 28.76 | 217.83 ± 30.74 | <0.001 | 199.57 ± 31.58 | 184.27 ± 30.8 | <0.001 | LDL-C (mg/dL) | 96.54 ± 24.32 | 121.5 ± 26.88 | <0.001 | 104.03 ± 27.5 | 94.58 ± 25.43 | 0.004 | HDL-C (mg/dL) | 45.89 ± 7.88 | 45.93 ± 7.58 | 0.97 | 45.9 ± 7.76 | 47.43 ± 6.84 | 0.203 | TC/HDL-C | 4.33 ± 1.16 | 4.9 ± 1.26 | 0.015 | 4.5 ± 1.22 | 3.98 ± 0.99 | <0.001 | LDL-C/HDL-C | 2.19 ± 0.79 | 2.74 ± 0.93 | 0.001 | 2.36 ± 0.87 | 2.05 ± 0.69 | 0.002 | hs-CRP (mg/L) | 0.64 (0.34, 1.36) | 2.31 (1.19, 5.52) | <0.001 | 0.83 (0.43–2.3) | 0.55 (0.33–1.35) | 0.009 |
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Data is expressed as mean ± SD, except for hs-CRP level. value was calculated at 95% confidence interval.
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