Research Article

Prevalence and Predictors of Thyroid Dysfunction in Patients with HIV Infection and Acquired Immunodeficiency Syndrome: An Indian Perspective

Table 3

Correlation between thyroid function parameters, CD4 cell count parameters, and vitamin-D in patients with HIV infection ().

Free T3Free T4TSHAnti-TPO antibody
Model-1Model-2Model-1Model-2Model-1Model-2Model-1Model-2

CD4 count (baseline)0.016 (0.759)−0.004 (0.947)0.004 (0.939)0.063 (0.271)0.024 (0.646)0.012 (0.836)−0.114 (0.031)−0.123 (<0.032)
CD4 count (6–12-month follow-up)−0.008 (0.878)−0.37 (0.520)0.041 (0.448)0.105 (0.067)−0.063 (0.237)−0.094 (0.101)−0.085 (0.113)−0.086 (0.131)
CD4 count (current)−0.085 (0.123)−0.098 (0.086)0.012 (0.833)0.045 (0.433)−0.111 (0.043)−0.113 (0.049)0.001 (0.981)−0.015 (0.789)
Serum 25OHD0.024 (0.651)0.028 (0.625)0.048 (0.368)−0.01 (0.856)−0.007 (0.900)−0.003 (0.952)−0.066 (0.216)−0.098 (0.086)

Model-1: without adjustment for any variable; Model-2: after adjustment for age and body mass index; not normally distributed; Spearman’s correlation coefficient calculated. All values expressed as correlation coefficient ( value); considered statistically significant; TSH: thyroid stimulation hormone; TPO: thyroid peroxidase; T3: tri-iodothyronine; T4: tetraiodothyronine.