Journal of Thyroid Research

Research Article

Bone Indices in Thyroidectomized Patients on Long-Term Substitution Therapy with Levothyroxine Assessed by DXA and HR-pQCT

Table 1

Baseline characteristics of all included patients on long-term treatment with levothyroxine and matched controls. Number of subjects () with percentages within group (%) or median with range (minimum–maximum).
 Patients
( = 49)		Controls
( = 49)		 value
Gender   
 Male, (%)9 (18)9 (18)  
 Female, (%)40 (82)40 (82)  
Age, yrs 55.6 (36.6–71.9)57.3 (36.5–73.8)0.73
BMI, kg/m227.5 (18.9–42.1)25.7 (19.4–37.1)0.33
Etiology   
 Nontoxic goiter, (%)16 (33)  
 Toxic goiter, (%)28 (57)  
 Thyroid cancer, (%)5 (10)  
Duration of disease, yrs11 (3–41)  
Treatment    
 Levothyroxine, (%)49 (100)0 (0) 
  Dose, µg/d 136 (50–357)— 
 Calcium, (%)21 (43)9 (18)0.009
  Dose, mg/d 800 (300–1600)800 (57–1000)0.53
 Vitamin D, (%)33 (67)18 (37)0.003
  Dose, µg/d 20 (5–45)20 (1.4–50)0.70
 Magnesium, (%)5 (10)1 (2)0.022
  Dose, mg/d 300 (150–370)14000.33