Morphological Diversity of Pretibial Myxedema and Its Mechanism of Evolving Process and Outcome: A Retrospective Study of 216 Cases

Table 2

Clinical manifestations of 6 variants when and before diagnosed at our department.

Variables	Total	Nodule	Plaque	Diffuse swelling	Mixture	Tumor	Elephantiasis	Statistical test	value
Patient number	216	45	33	96	17	10	15
PTM course
month	27.6 ± 37.6	24.48 ± 29.06	25.3 ± 31.8	26.8 ± 36.2	30.4 ± 38.9	22.2 ± 20.8	48.0 ± 45.2	= 1.231	0.296
Range (min–max) month	0.67–192	0.67–120	1–120	1–192	1–144	12–72	6–180
Symptom
Pruritus (number)	116/216 (53.7%)	25	16	50	8	4	13	= 8.137	0.149
Hyperhidrosis (number)	97/216 (44.91%)	8	10	42	15	8	14	= 48.379	0.000
Hypertrichosis (number)	65/216 (30.09%)	10	12	28	5	3	7	= 3.944	0.558
Orange peel-like appearance (number)	108/216 (50%)	14	23	49	9	5	8	= 11.711	0.039
Local injury history
Yes (number)	65	12	7	25	7	4	10	= 13.234	0.021
No (number)	151	33	26	71	10	6	5
Scars on lesions
Yes (number)	104	14	15	49	9	5	12	= 11.915	0.036
No (number)	112	31	18	47	8	5	3
PTM relapse
Yes (number)	72	16	9	35	6	3	3	= 2.347	0.799
No (number)	144	29	24	61	11	7	12
Stages
Active	185	36	30	84	16	8	11	= 16.543	0.347
Stable	17	5	3	5	1	2	1
Scerotic	2			1			1
Receding	12	4		6			2