Morphological Diversity of Pretibial Myxedema and Its Mechanism of Evolving Process and Outcome: A Retrospective Study of 216 Cases

Table 4

Serum TRAb levels at 4 stages of 6 variants at diagnosis of PTM.

Variables	Total	Nodule	Plaque	Diffuse swelling	Mixture	Tumor	Elephantiasis	Statistical test	value
Patient number	216	45	33	96	17	10	15
TRAb
(IU/L)	115.89 ± 148.41	66.61 ± 121.70	103.77 ± 102.79	136.48 ± 142.32	122.27 ± 129.47	48.61 ± 31.26	196.22 ± 298.39	= 2.817	0.017
min–max (IU/L)	2.04–1186.20	2.04–827	18.07–418.66	6.22–789.18	4.86–525.21	12–103	3.11–1186.20
Active stage
Number	185	36	30	84	16	8	11
TRAb ( IU/L)	130.12 ± 155.08	76.48 ± 134.17	111.27 ± 104.93	149.51 ± 146.08	129.61 ± 130.01	57.32 ± 28.67	262.72 ± 326.12	= 3.379	0.006
min–max (IU/L)	5–1186.20	5–827	21.71–418.66	19.9–789.18	29.74–525.21	26.64–103.00	39.08–1186.2
Stable stage
Number	17	5	3	5	1	2	1
TRAb ( IU/L)	17.64 ± 18.14	25.28 ± 29.98	28.69 ± 10.98	10.40 ± 4.92	4.86	13.76 ± 2.49	3.11
min–max (IU/L)	2.04–75	2.04–75	18.07–40.00	6.22–18.63	4.86–4.86	12–15.52	3.11–3.11
Sclerotic stage
Number	2			1			1
TRAb ( IU/L)	80.09 ± 68.19			128.3			31.87
min–max (IU/L)	31.87–128.3			128.3			31.87
Receding stage
Number	12	4		6			2
TRAb ( IU/L)	41.59 ± 52.16	29.44 ± 12.13		60.5 ± 70.19			9.17 ± 3.22
min–max (IU/L)	6.89–161.00	18–40		7.3–161.00			6.89–11.44

a: TRAb levels among active, stable, sclerotic, and receding, , .