Does the Polymorphism in the Length of the Polyalanine Tract of FOXE1 Gene Influence the Risk of Thyroid Dysgenesis Occurrence?

Table 4

Allele frequency to the polymorphism in the length of the polyA tract of FOXE1 gene in the present study and literature.

Alleles	Present study		Macchia et al. 1999	Hishinuma et al. (2001)		Polak et al. (2004)		Tonacchera et al. (2004)		Watkins et al. 2006		Santarpia et al. (2007)
	Brazil		Italy^†	Japan		France		Italy		New Zealand	Slovenia	Italy
	TD	C		TD	C	TD	C	TD	C			TD	C
11	1.1	0	0	0.4	0	0	0	0.9	0	0	0	0	0
12	1.1	1.5	2	1.3	0	1	0	0.9	0	0.4	0.6	1.1	0
14	96.7	60.7	54	78.3	97	85.3	65.1	81.6	88.7	67.5	67.2	82.2	94.7
16	1.1	36.6	40	17.4	3	13.7	33.7	16.6	11.3	30	28.4	16.1	5.3
17	0	0.8	4	1.7	0	0	1.2	0	0	0	0	0.6	0
19	0	0.4	0	0.9	0	0	0	0	0	2.1	3.8	0	0

Statistically significant difference in relation to the TD group of the present study [Control (present study)—; Macchia et al.—; TD (Hishinuma et al.)—; TD (Polak et al.)— and Control (Polak et al.)—; TD (Tonacchera et al.)— and Control (Tonacchera et al.)—; New Zealand (Watkins et al.)—; Slovenia (Watkins et al.)—; DT (Santarpia et al.)—].