Research Article

Thyroid Disorders in Central Ghana: The Influence of 20 Years of Iodization

Table 3

Temporal trends in incidence and characteristics of thyroid admissions in Central Ghana from 1982 to 2014.

Characteristics1982–19891990–19992001–20092010–2014 value

Number1152229037533240<0.0001
Incidence100,000 admissions212229417648<0.0001
Age/yearsMean43.3 (18.5)44.8 (18.8)41.3 (14.1)43.1 (15.3)0.7
Median43 (30–56)40 (28–60)40 (30–50)42 (31.5–53)0.06
Women number (%)638 (54.9)1456 (66.3)2931 (78.1)2631 (81.2)0.0004
HypothyroidismE0 3.9237 (20.4)419 (18.3)188 (5.0)68 (2.1)<0.0001
Nontoxic diffuse goiterE0 4.066 (5.7)46 (2.0)480 (12.8)113 (3.5)0.39
Nontoxic thyroid noduleE0 4.141 (3.5)121 (5.3)274 (7.3)113 (4.4)0.02
Nontoxic MNGE0 4.2595 (51.2)964 (42.1)544 (14.5)363 (11.2)<0.0001
Toxic MNGEO 5.248 (4.1)176 (7.7)1.066 (28.4)1260 (38.9)<0.0001
Toxic adenoma2 (0.3)32 (1.4)109 (2.9)136 (4.2)<0.0001
Diffuse toxic goiterE0 5.050 (4.3)137 (6.0)454 (12.1)713 (22.0)<0.0001
Thyroiditis unspecifiedEO 6.912 (2.1)30 (2.9)34 (2.6)27 (2.5)<0.12
Autoimmune thyroiditisE0 6.324 (3.8)66 (5.4)198 (5.1)324 (10.0)<0.00001
Unspecified thyroid/other diseaseE0 7.940 (3.4)57 (2.5)161 (4.3)62 (1.9)0.32