Symptomatic Primary Hyperparathyroidism as a Risk Factor for Differentiated Thyroid Cancer

Table 2

Characteristics of patients with severe primary hyperparathyroidism, with and without thyroid cancer.

	With thyroid cancer	Without thyroid cancer	P
	n= 12	n=47
Age	62 ± 9.5	52±15.8	0.03
Female gender	11 (92%)	35 (76%)	0.20
Autoimmune thyroid disease	4 (33%)	7 (15%)	0.10
Calcium (mg/dl)	11.8 (10.9-12.5)	11.4 (11-12.1)	0.90
Phosphorus (mg/dl)	2.6± 0.4	2.5±0.4	0.20
PTHi (pg/ml)	224 (130-460)	144 (115-227)	0.10
Vitamin D (ng/ml)	15± 5.4	14.9± 5.3	0.20
Urinary calcium in 24 hours (mg/24-hour)	318 (245-345)	319(210-400)	0.78
Creatinine clearance (ml/min)	73±20.9	81.7±28.6	0.20