Tumor Volume Kinetic Analyses Might Explain Excellent Prognoses in Young Patients with Papillary Thyroid Carcinoma
Table 2
Clinical presentation and measurements of 20 cases followed for more than 3 months.
Case
Sex
Age at diagnosis (years)
Initial measurements of the tumor (mm)
Final measurements of the tumor (mm)
Follow-up period (months)
Number of measurements
TV-DR (/year)
hTV-DR (/year)
D1
D2
D3
D1
D2
D3
1
F
19
32
25
24
33
22
19
4
2
−1.21
1.71
2
M
19
26
16
16
25
16
13
3
2
−1.20
1.69
3
F
19
9
6
9
8
6
7
7
2
−0.91
1.48
4
M
16
24
20
17
26
17
16
3
2
−0.80
1.99
5
F
19
21
15
13
20
15
9
40
6
−0.17
1.64
6
F
15
16
12
10
15
14
12
6
4
−0.13
2.01
7
F
18
7
6
6
6
6
5
30
6
−0.08
1.53
8
F
18
12
9
8
14
8
8
4
3
0.09
1.64
9
F
18
10
9
7
12
10
10
51
10
0.25
1.59
10
F
15
18
17
14
20
18
13
5
2
0.28
2.07
11
F
18
9
8
6
15
10
8
60
7
0.30
1.53
12
F
17
27
20
17
29
20
17
3
2
0.39
1.86
13
F
19
16
10
11
17
10
12
5
2
0.50
1.61
14
F
15
10
7
6
13
7
6
5
2
0.90
1.84
15
F
16
7
5
7
7
6
7
3
2
0.91
1.70
16
F
16
31
17
16
29
19
18
3
2
0.92
1.94
17
M
19
44
38
28
43
42
34
3
2
1.21
1.81
18
F
12
29
24
15
35
24
16
3
2
1.36
2.66
19
F
18
17
12
10
19
14
12
4
2
1.73
1.70
20
F
13
8
4
4
15
12
7
19
4
1.89
1.96
D1: maximum tumor diameter, D2: diameter perpendicular to the maximum tumor diameter, and D3: depth (mm). TV-DR: tumor volume-doubling rate; hTV-DR: hypothetical tumor volume-doubling rate before presentation. Cases 7, 9, and 11 were under active surveillance at the end of the study period. Cases 5 and 20 underwent thyroidectomy after 19 and 40 months of follow-up, respectively.
