Research Article

Microscopic Positive Tumor Margin Increases Risk for Disease Persistence but Not Recurrence in Patients with Stage T1-T2 Differentiated Thyroid Cancer

Table 4

Outcomes, positive versus clear margins, T1 and T2 stage.

Total n = 963Positive margins n = 112Clear margins n = 851 value

Follow-up
 Years of follow-up median (range)7 (3–20)6 (3–19)7 (3–20)0.570

After initial management
 Disease free933 (97%)103 (92%)830 (98%)0.001
 Persistent disease30 (3%)9 (8%)21 (2%)

During follow-up
 Recurrence12 (1%)1 (1%)11 (1%)0.760

At last visit
 Persistent disease18 (2%)4 (4%)14 (2%)0.240
 Disease-free945 (98%)108 (96%)837 (98%)

Data are presented as number (percentages), unless otherwise specified. Recurrence percentage based on the number of disease free excluding the persistent disease. Positive versus clear margins.