Research Article
Prognostic Significance of Thyroglobulin Antibodies in Differentiated Thyroid Cancer
Table 2
Characteristics of the patients with disease recurrence according to thyroglobulin autoantibodies levels during the follow-up.
| | TgAb | Stable | >50% increase | de novo appearance |
| | Sex (M/F) | M | F | F | F | F | F | F | | Age (years) | 50 | 73 | 38 | 52 | 77 | 70 | 75 | | Histology | Papillary | Papillary | Papillary | Papillary | Papillary | Papillary | Papillary | | Initial TNM | T3N1M0 | T4N1M0 | T2N1M0 | T4N1M1 | T4N1M0 | T4N1M0 | T3N1M0 | | Diagnostic procedure | PET/TC | PET/TC | Ultrasound | PET/TC | PET/TC | Ultrasound | Ultrasound | | Recurrence location | Lung M1 | Lung M1 | Neck N1 | Lung M1 | Lung M1 | Neck N1 | Neck N1 | | Recurrence time (months) | 12 | 14 | 7 | 23 | 36 | 48 | 23 | | Tg (ng/ml) | | Initial | 0.2 | 5.8 | 0.4 | 0.2 | 0.2 | 176 | 0.2 | | Recurrence | 0.1 | 0.6 | 0.1 | 0.2 | 0.2 | 19 | 0.3 | | TgAb (IU/ml) | | Initial | 128 | 3000 | 81 | 900 | 221 | Negative | Negative | | Recurrence | 83 | 2500 | 71 | 700 | 2500 | 63 | 172 |
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PET/TC: 18F-fluorodeoxyglucose positron emission tomography/computed tomography; Tg: thyroglobulin; TgAb: thyroglobulin autoantibodies; N1: lymph node metastasis; M1: distant metastasis.
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