Research Article

Immunohistochemical Analysis of Toll-Like Receptors, MyD88, and TRIF in Human Papillary Thyroid Carcinoma and Anaplastic Thyroid Carcinoma

Figure 4

Representative images of TLR5 expression in NH, PTC, and ATC. Moderate TLR5 staining was identified in NH in the cytoplasm or partially in the nucleus. Reduced expression was observed in PTC and ATC. HE: hematoxylin and eosin staining; IHC: immunohistochemistry; NH: nodular hyperplasia; PTC: papillary thyroid carcinoma; ATC: anaplastic thyroid carcinoma. Scale bar: 50 μm. (a) HE of NH. (b) Moderate intensity of IHC for TLR5 in NH. (c) HE of PTC. (d) Weak intensity of IHC for TLR5 in PTC. (e) HE of ATC. (f) Weak intensity of IHC for TLR5 in ATC. (g) TLR5 IHC scores in NH, PTC, and ATC. The IHC scores were significantly reduced in PTC and ATC compared to NH ( and , respectively). and .
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