A Comprehensive Review of Immunosuppression Used for Liver Transplantation

<table class="table-group" id="tab4"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td align="left">Immunosuppressive agent</td><td align="left">Target pathway</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td align="left">FK778</td><td align="left">Interferes with pyrimidine metabolism and DNA synthesis</td></tr><tr><td align="left">JAK inhibitors</td><td align="left">Interfere with Signal 3 transduction</td></tr><tr><td align="left">FTY720</td><td align="left">Inhibits T cell migration to venule endothelial cells in secondary lymphoid tissue</td></tr><tr><td align="left">LEA29Y</td><td align="left">Interferes with Signal 2 via inhibition of B7/CD28 interaction</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Investigational immunosuppressive agents in liver transplantation.

Journal of Transplantation

tab4

Table 4

Table 4: A Comprehensive Review of Immunosuppression Used for Liver Transplantation 