Clinical Study

Outcome and Prognostic Indicators of Patients with Hematopoietic Stem Cell Transplants Admitted to the Intensive Care Unit

Table 1

Clinical characteristics of HSCT patients requiring ICU admission.

CharacteristicsHSCT patients requiring ICU ( )

ICU admissions, 179
Type of transplant, (%)
Autologous59 (38%)
Allogeneic95 (62%)
Age, mean (SD)44 ( 14)
Days post-HSCT, median (IQR)48 (11, 208)
ICU days, median (IQR)5 (2, 11)
Gender, n (%)
Male91 (59%)
Female63 (41%)
Underlying disease, n (%)
Acute myeloid leukemia45 (29%)
Non-hodgkin's lymphoma32 (21%)
Acute lymphoblastic leukemia25 (16%)
Hodgkin's lymphoma17 (11%)
Multiple myeloma9 (6%)
Chronic myeloid leukemia7 (4.5%)
Breast cancer4 (2.6%)
Myelodysplastic syndrome4 (2.6%)
Aplastic anemia3 (1.9%)
Paroxysmal nocturnal hemaglobinuria2 (1.3%)
Chronic lymphoblastic leukemia2 (1.3%)
Other4 (2.6%)
Source of stem cell
Peripheral stem cell transplant139 (90%)
Bone marrow transplant14 (9.0%)
Cord blood1 (0.6%)
GVHD, n (% of Allo HSCT)65 (68%)
Neutropenia66 (43%)
Mechanical ventilation110 (71%)
Vasopressors104 (66%)
Dialysis63 (41%)