The Alpha-Melanocyte Stimulating Hormone Induces Conversion of Effector T Cells into Treg Cells
Figure 2
Flow cytometry analysis of LAP expression on -MSH-induced Treg cells. The T cells were collected and treated as in Figure 1, but were costained for CD25 and LAP. The flow cytometry results are presented as dot plots showing T cells expressing CD25 and LAP representing the results of two independent experiments. The expression of LAP on the effector T cells decreases relative to the resting T cells. In contrast, there is more than a 10-fold increase in LAP expression on -MSH-induced Treg cells compared to the effector T cells.