Impact of Acute Rejection on Kidney Allograft Outcomes in Recipients on Rapid Steroid Withdrawal

Table 4

Findings on followup 1-year protocol biopsy.

	No rejection; (𝑛=214)	SR; (𝑛=35)	CR; (𝑛=19)
% of group with 1-year protocol biopsy	57%	76%	53%
Days from rejection to biopsy (median)		223	336*
	Banff scores (mean value)
Interstitial inflammation (i)	0.11	0.83^*#	0.35^*#
Tubulitis (t)	0.16	0.66*	0.59*
Glomerulitis (g)	0.08	0.26	0.18
Interstitial fibrosis (ci)	0.97	1.43^#	1.06
Tubular atrophy (ct)	1.18	1.51^#	1.24
Intimal thickening (cv)	0.59	0.43	0.56
Transplant glomerulopathy (cg)	0.01	0.11^#	0.06
IFTA > 2 and i/t > 0	8%	34%̂‌	24%**

SAR: subclinical acute rejection, CAR: clinical acute rejection, AR: acute rejection, IFTA: interstitial fibrosis and tubular atrophy (sum of Banff ci plus ct score).
* 𝑃<.05 comparing CAR to SAR.
^#𝑃<.05 compared to No rejection.
^{^}̂𝑃<.0001 comparing SR to No rejection.
** 𝑃=.02 comparing CR to No rejection.