Intraoperative Hyperglycemia Augments Ischemia Reperfusion Injury in Renal Transplantation: A Prospective Study

Table 1

(a) Univariate models of percentage change in NGAL.

Characteristic	β Coefficient	95% Confidence interval	𝑃-value
Recipient age (per 10 years)	0.07	0.02 to 0.11	<0.01
Recipient gender (male)	0.12	−0.01 to 0.25	0.07
Recipient race (compared to white)
Black	−0.13	−0.33 to 0.07	0.20
Hispanic	−0.14	−0.29 to 0.01	0.07
Asian/Pacific Islander	−0.08	−0.38 to 0.22	0.59
Blood glucose (per 10 unit increase)	0.02	0.01 to 0.03	<0.01
Blood glucose > 160 mg/dL	0.19	0.04 to 0.33	0.02
Recipient diabetes	0.18	0.07 to  0.30	<0.01
Panel reactive antibody	−0.12	−0.38 to 0.14	0.36
Recipient body mass index	0.01	−0.001 to 0.02	0.09
Warm ischemic time (>30 min)	0.14	−0.01 to 0.28	0.06
Intra-operative IVF (per liter)	0.03	−0.06 to 0.12	0.49
Thymoglobulin induction (compared to Simulect)	0.002	−0.15 to 0.15	0.97
Donor age (per 10 years)	0.05	−0.01 to 0.1	0.10
Donor gender (male)	−0.02	−0.15 to 0.12	0.79
Donor race (compared to caucasian)
Black	−0.12	−0.33 to 0.08	0.24
Hispanic	−0.11	−0.27 to 0.05	0.18
Asian/Pacific Islander	−0.11	−0.37 to 0.14	0.38
Donor BMI	−0.005	−0.02 to 0.01	0.62

(b) Multivariate model of percentage change in NGAL.

Characteristic	β Coefficient	95% Confidence interval	𝑃-value
Blood glucose > 160 mg/dL	0.19	0.06 to 0.33	<0.01
Warm ischemic time (>30 min)	0.11	−0.04 to 0.25	0.13
Recipient age (per 10 year increase)	0.05	0 to 0.10	0.05