Journal of Transplantation / 2012 / Article / Fig 1

Research Article

c-Jun-N-Terminal Kinase Signaling Is Involved in Cyclosporine-Induced Epithelial Phenotypic Changes

Figure 1

Cyclosporine (CsA) activates JNK signaling. (a) Representative western blot of JNK and p-JNK expression in primary cultures of HRECs exposed to the vehicle or 6 μM CsA for various incubation times. (b) Real-time PCR analysis of EGR1 mRNA expression in cells that were exposed to 6 μM CsA with or without the 2 μM JNK inhibitor (L)-JNKI1.