Journal of Transplantation / 2012 / Article / Tab 1

Clinical Study

Urinary NGAL Ratio Is Not a Sensitive Biomarker for Monitoring Acute Tubular Injury in Kidney Transplant Patients: NGAL and ATI in Renal Transplant Patients

Table 1

Demographic and clinical data of patients with and without ATI.

ATIATI+ All patients value

Recipient
 Age (years)49 ± 12 (49,20–69)51 ± 12 (52,25–73)51 ± 12 (50,20–73)
 Gender (% m/f)65,7/34,361,9/38,162,9/37,1
 Retransplanted pat. (%)8,610,510,0
 Preformed antibodies neg. (%)94,393,393,5
 Lowest s-creatinine within the first 6 weeks of tx160 ± 83182 ± 87176 ± 86
 Hypercholesteroemia before tx (%)31,437,135,7
 Arterial hypertension before tx (%)10096,297,1
Donor
 Age (years)47 ± 15 (50,7−70)51 ± 13 (52,16–77)50 ± 14 (51,7–77)
 Gender (% m/f)60/4053,3/46,755/45
 Type
  Deceased (%)82,995,292,10.029
  Living (%)17,14,87,9
 CMV IgG positive (%)6053,855,4
 s-creatinine (μmol/L)95 ± 3693 ± 4493 ± 42
Graft factors at tx
 Cold ischemia time (h)14 ± 717 ± 717 ± 70.032
 Mean number of HLA mismatches2,26 ± 1,62,4 ± 1,722,36 ± 1,68
 Initial function of the graft (%)68,628,638,60.000
 Need of dialysis following tx (%)31,471,462,10.000
 Immunosuppressive regimen (%)
  CyA-MMF-Steroids-IL237,13132,6
  CyA-MMF-Steroids-ATG010,7
  CyA-MMF-Steroids-no induction032,2
  CyA-MMF-IL214,33126,7
  CyA-MMF-ATG010,7
  Other, IL228,61417,8
  Other, ATG11,478,1
  Other, no induction8,61211,1

ATI−: patients without ATI; ATI+: patients with ATI; tx: transplantation; median and range of values in brackets; CyA: cyclosporine A; MMF: mycophenolate mofetil; ATG: antithymocyte globulin; IL2: interleukin 2 receptor antagonist.

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