Neutrophil Gelatinase-Associated Lipocalin in Kidney Transplantation Is an Early Marker of Graft Dysfunction and Is Associated with One-Year Renal Function

Table 2

Serial levels of serum creatinine and uNGAL through the first posttransplant week, according to graft function (delayed or prompt).

Serum Creatinine (mg/dL); Median, (IQR)	Prior transplantation	1st day*; (𝑛=40, 18 DGF)	2nd day; (𝑛=40, 18 DGF)	4th day; (𝑛=40, 18 DGF)	7th day; (𝑛=40, 18 DGF)
DGF (𝑛=18)	7.5; (6.0–11.7)	8.2; (6.5–9.3)	7.5; (5.9–8.5)	6.9; (6.1–8.0)	6.4; (5.3–8.9)
Non-DGF (𝑛=22)	7.8; (5.1–9.4)	6.3; (4.6–7.9)	4.3; (2.8–6.1)	2.5; (1.6–3.2)	1.9; (1.4–2.4)
Urine NGAL (ng/mL); Median, (IQR)	3 to 6 h after surgery; (𝑛=30, 13 DGF)	1st day*; (𝑛=35, 14 DGF)	2nd day; (𝑛=35, 15 DGF)	4th day; (𝑛=36, 15 DGF)	7th day; (𝑛=35, 16 DGF)
DGF (𝑛=18)	647; (328–1648)	866; (500–1256)	834; (510–2632)	851; (549–1643)	407; (106–1249)
Non-DGF (𝑛=22)	256; (105–446)	129; (64–306)	80; (29–138)	47; (36–91)	34; (26–57)

∗1st day = 8 to 12 h after surgery; values are medians and interquartile range (25th to 75th percentile).
Abbreviations: uNGAL: urinary neutrophil gelatinase associated lipocalin; IQR: interquartile range; DGF: delayed graft function; non-DGF: prompt function.