Research Article

Neutrophil Gelatinase-Associated Lipocalin in Kidney Transplantation Is an Early Marker of Graft Dysfunction and Is Associated with One-Year Renal Function

Table 6

Association of uNGAL with delayed graft function by multivariable analysis (logistic regression).

Delayed graft function
OR adjusted* value 95% CI

Model 1 (uNGAL at 3 to 8 h after surgery)
 uNGAL0 (per 50 ng/mL of increase)1.150.0441.01–1.31
 Recipient age (per 5 years of increase)1.490.0540.99–2.24
Model 2 with (uNGAL at day 1)
 uNGAL1 (per each 50 ng/mL of increase)1.220.0121.05–1.42
 Recipient age (per 5 years of increase)1.990.0221.11–3.57
Model 3 (uNGAL at day 2)
 uNGAL2 (per each 50 ng/mL of increase)1.350.0041.10–1.66
Model 4 (uNGAL at day 4)
 uNGAL4 (1 ng/mL increase)3.010.0351.08–8.40
Model 5 (uNGAL at day 7)
 uNGAL7 (per each 50 ng/mL of increase)1.430.0501.01–2.04
 Recipient age (per 5 years of increase)1.730.0381.03–2.90

Note: results given by logistic regression (backward Wald test).
Abbreviations: OR: odds ratio; 95% CI (95% confidence interval); uNGAL: urinary neutrophil gelatinase-associated lipocalin.
*Adjusted for pretransplant time on dialysis, recipient gender and age, and donor age.