Journal of Transplantation / 2013 / Article / Tab 1

Clinical Study

Circulating CD4+CD28null T Cells May Increase the Risk of an Atherosclerotic Vascular Event Shortly after Kidney Transplantation

Table 1

Demographic and clinical characteristics of patients receiving a kidney allograft with or without an atherosclerotic vascular event in the first year after transplantation.

Atherosclerotic event in the first year after kidney transplantation value
NoYes

Number of patients27020
Age (median and IQR in years)52 (40–62)62 (47–67)0.02
Male gender69.3%75%0.59
Non-Western European origin27.6%35%0.48
CMV seropositive103/1673/170.052
Cumulative years on dialysis treatment (median and interquartile range)1.4 (0–3)1.7 (1–4)0.49
History of atherosclerotic disease24.3%75%<0.001
 Cardiovascular14.9%52.6%<0.001
 Cerebrovascular7.9%25%0.02
  Aorta/peripheral arteries6.7%15.8%0.15
Underlying kidney disease0.61
 Hypertensive nephropathy30.2%42.1%
 Primary glomerulopathy24.3%21.1%
 Diabetic nephropathy10.8%5.3%
 Polycystic kidney disease11.9%21.1%
 Other16.0%10.5%
 Unknown6.7%0.0%
Prevalence of risk factors for atherosclerosis
 Hypertension87.1%94.4%0.36
 Hyperlipidaemia43.7%90.9%<0.001
 Smoking33.6%50.0%0.18
 Diabetes mellitus22.1%31.6%0.58
% CD4+CD28null T cells (mean SD) % %0.01
CD4+CD28null T cell × 104/mL
(mean SD)
0.23