Research Article
Molecular Signatures of Recurrent Hepatocellular Carcinoma Secondary to Hepatitis C Virus following Liver Transplantation
Table 1
Patient characteristics: clinical characteristics of the 16 patients from tumor recurrence and tumor nonrecurrence groups (mean ± SD or proportion).
| | Study group | HCC-R group | HCC-NR group | P-value |
| | Number | 8 | 8 | | | Age, years | | | 0.1 | | Male gender | 100% | 100% | 1 | | Race | | | | | Caucasian | 75% | 100% | 0.2
| | Asian | 12.5% | 0% | | Alaska native | 12.5% | 0% | | BMI* | | | 0.5 | | AFP level, mg/dL** | | | 0.07 | | Cirrhosis, postnecrotic-type C | 100% | 100% | 1 | | Prior HCV treatment | 75% | 50% | 0.3 | | Prior HCC treatment | 37.5% | 0% | 0.2 | | Hours to process*** | | | 0.06 | | Largest diameter Tumor, cm | | | 0.1 | | Number of tumors | | | | | 1 | 25% | 50% | 0.2 | | 2 | 25% | 12.5% | | (3–5) | 0% | 37.5% | | ≥6 | 50% | 0.0% | | Tumor in both lobes | 37.5% | 12.5% | 0.6 | | Histology | | | | | Poorly differentiated | 75% | 0% | <0.01
| | Moderately differentiated | 25% | 75% | | Well differentiated | 0% | 25% | | Macroinvasion | 50% | 0% | 0.08 |
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Body mass index; **alpha-fetoprotein level.
***Time specimens removed in surgical procedure until being fixed in formalin.
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