Peak Serum AST Is a Better Predictor of Acute Liver Graft Injury after Liver Transplantation When Adjusted for Donor/Recipient BSA Size Mismatch (ASTi)

Table 2

Analyses of cases with different predictive results for PNF by conventional UNOS criteria and ASTi criteria.

				Conventional criteria						ASTi criteria
	PNF	AST	PT-INR	AST 3,000	Results		BSAi	ASTi	PT-INR	ASTi 3,500	Results
	(Yes: 1, no: 0)	(mg/dL)	(—)	PT-INR 2.5			(—)	(mg/dL)	(—)	PT-INR 2.3
Case 1	0	3256	2.3^∗	0	TN	Small-for-size	0.69	4745	2.3	1	FP
Case 2	1	4500	2.3	0	FN	Small-for-size	0.69	6556	2.3^∗	1	TP
Case 3	0	3233	3.9	1	FP	Small-for-size	0.99	3249^∗	3.9	0	TN
Case 4	0	4500	2.4^∗	0	TN	Large-for-size	1.02	4430	2.4	1	FP
Case 5	0	3308	3.1	1	FP	Large-for-size	1.05	3137^∗	3.1	0	TN
Case 6	0	3469	2.8	1	FP	Large-for-size	1.12	3105^∗	2.8	0	TN
Case 7	0	3760	5.0	1	FP	Large-for-size	1.17	3207^∗	5.0	0	TN

Results for prediction of PNF by two different prediction criteria. Bold font shows the favorable results compared to results of the other criteria. ∗In PT-INR or AST, ASTi represent the factors, which were responsible for improvement in results. First three cases had small-for-size donors and last four cases had large-for-size donors. AST: aspartate aminotransferase, BSAi: body surface area index, FN: false negative, FP: false positive, PNF: primary nonfunction of graft, PT-INR: international normalized ratio of prothrombin time, TN: true negative, and TP: true positive.