Risk-Stratified Cardiovascular Screening Including Angiographic and Procedural Outcomes of Percutaneous Coronary Interventions in Renal Transplant Candidates
Table 4
Unadjusted and adjusted HR for predictors of MACE after wait listing.
Variable
Unadjusted hazard ratio
Adjusted hazard ratioa
value
HR (95% CI)
value
HR (95% CI)
Patient characteristics
Highrisk
0.004
8.16 (1.97–33.79)
Age
<0.001
1.05 (1.03–1.08)
0.003
1.05 (1.02–1.08)
Previous transplantation
0.694
1.16 (0.55–2.43)
Smoking
0.021
2.10 (1.12–3.93)
Gender
0.335
1.41 (0.70–2.80)
Diabetes
0.002
2.61 (1.41–4.85)
History of CAD
<0.001
4.32 (2.30–8.08)
0.042
2.09 (1.03–4.24)
History of CVD
<0.001
4.94 (2.07–11.77)
0.018
2.96 (1.20–7.31)
History of PVD
<0.001
4.20 (2.13–8.28)
BMI (kg/m2)
0.153
0.95 (0.88–1.02)
Time on dialysis before wait listing
0.001
1.01 (1.00-1.01)
0.004
1.01 (1.00-1.01)
Screening/intervention
LV hypertrophy
0.735
0.87 (0.38–2.00)
Positive stress test (28 of 154 conclusive stress tests)
0.018
2.79 (1.19–6.53)
Significant coronary artery stenosis (38 of 58 coronary angiographies)
0.039
1.49 (1.02–2.17)
Coronary intervention (PCI or CABG; 18 of 58 coronary angiographies)
0.202
1.78 (0.74–4.29)
Final model determined by Cox regression with stepwise selection. CAD: coronary artery disease; CVD: cerebrovascular disease; PVD: peripheral vascular disease; LV hypertrophy: left ventricular hypertrophy; BMI: body mass index.
