Delayed Graft Function in Kidney Transplants: Time Evolution, Role of Acute Rejection, Risk Factors, and Impact on Patient and Graft Outcome

Table 4

Multivariable logistic regression analysis of factors predicting acute rejection episodes occurring during the delayed graft function period in 1784 transplants performed from 1983 to 2014.

Predictive factors	Risk code	Regression coefficient	value	Odds ratio (95% CI)
Constant		−2.119	<0.001
Peak HLA sensitization (>50% PRA)	If yes, then 1, else 0	1.265	<0.001	3.5 (2.4–5.2)
Duration of regular dialyses (years)	Increase per year	0.098	<0.001	1.103 (1.062–1.146)
Antilymphocyte globulin induction	If no, then 1, else 0	0.860	<0.001	2.4 (1.6–3.4)
Recipient’s age (years)	Decrease per year	−0.025	<0.001	0.975 (0.961–0.989)
HLA-A+B+DR mismatches (MM)	Increase per MM	0.206	<0.001	1.22 (1.09–1.39)
Recipient’s perioperative saline loading	If no, then 1, else 0	0.624	0.005	1.9 (1.2–2.9)
Use of mycophenolate mofetil	If no, then 1, else 0	0.630	0.007	1.9 (1.2–2.9)

Log likelihood chi-square (7 DF): 238.18, . Goodness of fit: .