Journal of Transplantation / 2015 / Article / Tab 1

Research Article

Influence of Deceased Donor and Pretransplant Recipient Parameters on Early Overall Kidney Graft-Survival in Germany

Table 1

Summary of donor characteristics and transplant variables used in univariate analyses of graft-survival after isolated kidney transplantation (KTX). For interval-scaled parameters absolute numbers, median, interquartile range, risk ratio (with 95% confidence interval), and values (Cox regression) are shown. For nominal and categorical parameters absolute numbers, proportions, the percentage of graft-failures, and values (log-rank test) are shown. All donor characteristics and transplant variables investigated are shown in supplementary Table e1.

Donor characteristics and basic donor dataUnit of analysis or factor level at risk(%)MedianInterquartile rangeGraft-failure (%) or hazard ratio [95% CI] value

AgeYear43925645–671.027 [1.021–1.033]<0.001
GenderFemale2085(47.3)14.0%0.490
Male2326(52.7)13.5%
Weightkg441180.070.0–90.00.998 [0.993–1.002]0.320
Sizecm4411172.0165.0–180.00.984 [0.977–0.992]<0.001
Stay in intensive care unitday7744.02.0–8.00.987 [0.970–1.005]0.148
Cause of deathCerebral hypoxia557(12.6)11.7%0.003
CVA (bleeding)2516(57.0)14.9%
Ischemic stroke497(11.3)14.7%
Other78(1.8)1.3%
Trauma763(17.3)11.9%
Cardiac resuscitation [10]None3876(87.8)14.0%0.094
Any535(12.1)11.8%

Procurement and allocation
Time of death until cross clamp
(i) With procurement of thoracic organsHour1900(43.1)12.310.0–15.90.988 [0.964–1.011]0.306
(ii) Without procurement of thoracic organsHour2511(56.9)8.86.6–11.40.985 [0.967–1.003]0.111
Ischemia timeMinute4411741.0544.0–946.01.000 [1.000–1.000]0.544
Preservation solutionHTK3804(86.2)13.7%0.217
UW597(13.5)13.9%
Other10(0.2)30.0%
Graft-quality at recoveryGood3965(90.7)12.8%<0.001
Poor or medium405(9.3)23.7%

Medication (at ET report)
Catecholamines
(actual)
No1138(25.8)16.2%0.016
Yes3273(74.2)12.9%
Catecholamines
within last 24 hours
No765(17.3)16.2%0.035
Yes3646(82.7)13.2%

Additional diagnosis
History of arterial hypertensionNot reported2568(58.2)12.3%0.001
Reported1843(41.8)15.7%
History of diabetesNot reported4240(96.1)13.6%0.097
Reported171(3.9)17.5%
History of coronary heart diseaseNot reported3584(81.3)13.3%0.027
Reported827(18.7)15.7%
History of smokingNot reported3177(72.0)14.3%0.181
Reported1234(28.0)12.4%
History of contact to cytomegaly virusAnti-CMV−1723(39.1)12.0%0.022
Anti-CMV+2688(60.9)14.8%

Laboratory data
Creatinine at admissionμmol/L440076.961.9–97.21.001 [1.000–1.003]0.104
Creatinine at ET reportμmol/L439979.661.9–1101.000 [0.999–1.002]0.389