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Journal of Transplantation
Volume 2015 (2015), Article ID 854640, 8 pages
http://dx.doi.org/10.1155/2015/854640
Research Article

A Nationwide Assessment of the Burden of Urinary Tract Infection among Renal Transplant Recipients

1School of Public Health, Loma Linda University, Loma Linda, CA 92350, USA
2William S. Middleton Memorial Veterans Hospital, Madison, WI 53705, USA
3Department of Health Science and Human Ecology, California State University San Bernardino, San Bernardino, CA 92407, USA
4Department of Medicine, University of Wisconsin, Madison, WI 53706, USA

Received 28 December 2014; Revised 12 February 2015; Accepted 15 February 2015

Academic Editor: Bernhard K. Krämer

Copyright © 2015 Benjamin J. Becerra et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. Evaluate the prevalence and outcomes of urinary tract infection (UTI) among renal transplant recipients. Methods. A secondary analysis of the Nationwide Inpatient Sample 2009–2011 was conducted. Survey-weighted multivariable regression analyses were used to examine the impact of UTI on transplant complications, total charges, and length of stay. Results. A total of 1,044 renal transplant recipients, representing a population estimate of 49,862, were included in the study. UTI was most common in transplant recipients with hypertension (53%) and prevalence was noted to be 28.2 and 65.9 cases per 1,000 for men and women, respectively. UTI increased the likelihood of transplant complications (182% for men, 169% for women). Total charges were 28% higher among men as compared to 22% among women with UTI. Such infection also increased the length of stay by 87% among men and 74% among women. Discussion. UTI in renal transplant recipients was associated with prolonged length of stay, total charges, and increased odds of transplant complications. Interventions to prevent UTI among such patients should be a priority area for future research and practice.