C1Q Assay Results in Complement-Dependent Cytotoxicity Crossmatch Negative Renal Transplant Candidates with Donor-Specific Antibodies: High Specificity but Low Sensitivity When Predicting Flow Crossmatch

Figure 5

Characteristics of DSA and FXM results. The first two lines show B cell and T cell channel shift results for each positive FXM test; the next line depicts complement fixing HLA-Abs (C1q+ in filled cells) where a dashed square mark indicates DSA C1q+. The next three lines show the mean DSA-SAB MFI, number of DSA, and dominant DSA-SAB MFI. MFI = mean fluorescence intensity, DSA = donor-specific antibodies, = number, C1q+ HLA-Abs = C1q positive HLA antibodies, and FXM = flow crossmatch.