Liver Transplantation for Hepatocellular Carcinoma: A Single Center Resume Overlooking Four Decades of Experience

Figure 10

(a) Proportion of vascular infiltration with respect to tumor grading (G). The incidence of vascular infiltration and the proportion of small (V1) and large (V2) infiltrated vessels increased with each step of tumor dedifferentiation () (). The overall incidence of vascular infiltration was 7%, 31%, and 48% for G1, G2, and G3-4 graded tumors, respectively. The proportion of small vascular infiltration (V1) was 5%, 12%, and 21% for G1, G2, and G3-4 graded tumors, respectively. The proportion of large vessel infiltration (V2) was 2%, 20%, and 27% for G1, G2, and G3-4 graded tumors, respectively. (b) Proportions of uninodular/multinodular tumors with unilateral/bilateral hepatic spreading in G1–4 graded tumors. There was a close correlation between tumor grading and intrahepatic tumor spreading. The proportion of multinodular and bilateral spread tumors increased with each step of tumor dedifferentiation () (). The proportion of uninodular tumors was 59%, 43%, and 27% for G1, G2, and G3-4 graded tumors, respectively. The proportion of multinodular/unilateral tumors was 26%, 26%, and 31% for G1, G2, and G3-4 graded tumors, respectively. The proportion of multinodular/bilateral tumors was 14%, 31%, and 42% for G1, G2, and G3-4 graded tumors, respectively.

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