Research Article

A Prognostic Tool for Individualized Prediction of Graft Failure Risk within Ten Years after Kidney Transplantation

Table 1

Immunological parameters, donor, recipient, and transplant characteristics (n=616).

Donor characteristics

Mean age (SD) [years]43.5 (16.4)
Age ≥60 years (n)110 (17.8%)
Cause of death (n)
Vascular268 (43.5%)
Traumatic vehicle accident106 (17.2%)
Traumatic nonvehicle accident116 (18.8%)
Others36 (5.8%)
Unknown90 (14.6%)

Recipient characteristics

Age (years, mean (SD))49.5 (13.8)
Male/female (n)375/241

Biological parameters

Mean proteinuria measured at M12 [g/L] (SD)0.166 (0.451)
Mean serum creatinine at month 12 [μmol/L] (SD)139 (67)

Clinical characteristics

Death with functioning graft (n)56 (9.1%)
Acute rejection (n)135 (21.9%)
Graft failure (n)68 (11.0%)

Initial immunosuppressant

AZA/MMF134/473
Unknown9

Immunological parameters

De novo donor specific anti-HLA antibodies (n)60 (9.7%)
Non–donor-specific anti-HLA before transplantation (n)96 (15.6%)

Transplant characteristics

Retransplantation (n)52 (8.5%)
Mean cold ischemia time [minutes] (SD)1138 (369)
Period of transplantation (n)
From 1984 to the end of 1993 99 (16.0%)
From 1994 to the end of 2002 194 (31.5%)
From 2003 to the end of 2011 323 (52.5%)

AZA = azathioprine; MMF = mycophenolate mofetil.