Research Article
A Prognostic Tool for Individualized Prediction of Graft Failure Risk within Ten Years after Kidney Transplantation
Table 1
Immunological parameters, donor, recipient, and transplant characteristics (n=616).
| Donor characteristics | |
| Mean age (SD) [years] | 43.5 (16.4) | Age ≥60 years (n) | 110 (17.8%) | Cause of death (n) | | Vascular | 268 (43.5%) | Traumatic vehicle accident | 106 (17.2%) | Traumatic nonvehicle accident | 116 (18.8%) | Others | 36 (5.8%) | Unknown | 90 (14.6%) |
| Recipient characteristics | |
| Age (years, mean (SD)) | 49.5 (13.8) | Male/female (n) | 375/241 |
| Biological parameters | |
| Mean proteinuria measured at M12 [g/L] (SD) | 0.166 (0.451) | Mean serum creatinine at month 12 [μmol/L] (SD) | 139 (67) |
| Clinical characteristics | |
| Death with functioning graft (n) | 56 (9.1%) | Acute rejection (n) | 135 (21.9%) | Graft failure (n) | 68 (11.0%) |
| Initial immunosuppressant | |
| AZA/MMF | 134/473 | Unknown | 9 |
| Immunological parameters | |
| De novo donor specific anti-HLA antibodies (n) | 60 (9.7%) | Non–donor-specific anti-HLA before transplantation (n) | 96 (15.6%) |
| Transplant characteristics | |
| Retransplantation (n) | 52 (8.5%) | Mean cold ischemia time [minutes] (SD) | 1138 (369) | Period of transplantation (n) | | From 1984 to the end of 1993 | 99 (16.0%) | From 1994 to the end of 2002 | 194 (31.5%) | From 2003 to the end of 2011 | 323 (52.5%) |
|
|
AZA = azathioprine; MMF = mycophenolate mofetil.
|