Table of Contents
Molecular Biology International
Volume 2011 (2011), Article ID 185413, 3 pages

Target Identification and Intervention Strategies against Kinetoplastid Protozoan Parasites

1Division of Infectious Diseases and Immunology, Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Jadavpur, Kolkata 700 032, India
2Instituto de Biofisica Carlos Chagas Filho, UFRJ Directoria de Programas do Inmetro, Rio de Janeiro 21941-902, Brazil
3Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA

Received 15 June 2011; Accepted 15 June 2011

Copyright © 2011 Hemanta K. Majumder et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. B. B. Das, A. Ganguly, and H. K. Majumder, “DNA topoisomerases of Leishmania: the potential targets for anti-leishmanial therapy,” Advances in Experimental Medicine and Biology, vol. 625, pp. 103–115, 2008. View at Google Scholar
  2. R. Balaña-Fouce , C. M. Redondo, Y. Pérez-Pertejo, R. Díaz-González, and R. M. Reguera, “Targeting atypical trypanosomatid DNA topoisomerase I,” Drug Discovery Today, vol. 11, no. 15-16, pp. 733–740, 2006. View at Google Scholar
  3. J. A. Urbina, “Lipid biosynthesis pathways as chemotherapeutic targets in kinetoplastid parasites,” Parasitology, vol. 114, supplement, pp. S91–S99, 1997. View at Google Scholar
  4. M. J. McConville, “The surface glycoconjugates of parasitic protozoa: potential targets for new drugs,” Australian and New Zealand Journal of Medicine, vol. 25, no. 6, pp. 768–776, 1995. View at Google Scholar
  5. C. R. Caffrey and D. Steverding, “Kinetoplastid papain-like cysteine peptidases,” Molecular and Biochemical Parasitology, vol. 167, no. 1, pp. 12–19, 2009. View at Google Scholar
  6. D. Horn, “Histone deacetylases,” Advances in Experimental Medicine and Biology, vol. 625, pp. 81–86, 2008. View at Google Scholar