Abstract
The secretion of tumour necrosis factor-α (TNFα),
interleukin-1α (IL-α) and interleukin-6 (IL-6) by a
human astrocytoma cell fine was studied 1 h, 3 h, 6 h and 24 h after
infection with tachyzoites from three Toxoplasma gondii
strains (virulent, RH; cystogentc, 76K and Prugniaud strains). The
astrocytoma cell fine constitutively secreted TNFα and IL-6,
but no IL-1α. A positive control was obtained by stimulation
with phorbol esters inducing a significant increase (