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Mediators of Inflammation
Volume 7, Issue 3, Pages 145-147

Cyclosporine and inflammatory bowel disease: buying time

Department of Gastroenterology and Internal Medicine II, University Hospital Rotterdam Dijkzigt, Dr Molewaterplein 40, Rotterdam NL-3015 GD, The Netherlands

Copyright © 1998 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Cyclosporine is an effective drug in acute exacerbations of corticosteroid resistant ulcerative colitis, but its efficacy to maintain disease remission is not clear. Cyclosporine may not be as effective in Crohn's disease. However, being a rapidly acting immunosuppressant, cyclosporine may be a valuable therapeutic option in the short-term to treat corticosteroid resistant Crohn's disease and ulcerative colitis.