Abstract
The study was aimed to compare inflammatory parameters between
carriers of apoE4 isoforms (apoE4/3, apoE4/2, and apoE4/4
phenotypes) and those of carrying apoE3 isoform without apoE4
isoform (apoE3/3 phenotypes and apoE2/3 phenotypes). The
concentrations of serum hsCRP, sVCAM-1, sICAM-1, and sE-selectin
were measured in 211 subjects from Finnish low-HDL families and in
157 normolipidemic subjects. The subjects with apoE4 isoform had
lower concentrations of serum hsCRP both in low-HDL family members
(