Mediators of Inflammation
Volume 2007 (2007), Article ID 72361, 9 pages
http://dx.doi.org/10.1155/2007/72361
Protecting Effects of Dexamethasone on Thymus of Rats with Severe Acute Pancreatitis
1Department of General Surgery, Hangzhou First People’s Hospital, Hangzhou, Zhejiang Province 310006, China
2Department of General Surgery, Second Affiliated Hospital Medical College, Hangzhou, Zhejiang Province 310003, China
3Zhejiang University of Traditional Chinese Medical, Hangzhou 310053, Zhejiang Province, China
Received 4 September 2007; Accepted 5 November 2007
Copyright © 2007 Zhang Xiping et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Purpose. To study the protecting effects of dexamethasone on thymus of rats with
severe acute pancreatitis (SAP).
Methods. The SAP rats were randomly assigned to the model group and
dexamethasone-treated group, the other normal healthy rats were assigned to the sham operation
group. The rat survival, thymus pathological changes, apoptotic index, as well as expression
levels of NF-