Clinical Study

Circulating Tissue Inhibitor of Matrix Metalloproteinase-4 (TIMP-4) in Systemic Sclerosis Patients with Elevated Pulmonary Arterial Pressure

Table 1

Characteristics of patients with systemic sclerosis (SSc).

All patientsDiffuse SScLimited SSc

Women/men ( )102/471/431/0
Mean age SD, 54 1352 13 56 12
years (range)(22–80)(22–80)(25–77)
Mean disease duration SD, 11 4 10 312 4
years (range)(2–25) (2–20)(2–25)

Medications, % of patients

Calcium—channel blockers77% (82)76% (57)81% (25)
Angiotensin—converting enzyme inhibitors55% (58)63% (47)31% (11)
Corticosteroids29% (31)35% (26)16% (5)
Cyclophosphamide22% (21)23% (17)13% (4)
Mycophenolate mofetil7% (7)8% (6)3% (1)