Lymphotoxin-𝛼 Plays Only a Minor Role in Host Resistance to Respiratory Infection with Virulent Type A Francisella tularensis in Mice

Figure 1

Comparison of the survival rates of LTα−/− (open circles) and LTα+/+ (closed circles) mice following aerosol inoculation with a low-dose of virulent type A F. tularensis. Groups of LTα−/− (n = 22) and LTα+/+ (n = 14) mice were challenged by aerosol with type A F. tularensis strain FSC033 (inhaled dose of ~10 organisms) and their survival was monitored daily.